The new Las Tablillas border crossing in Los Chiles de Alajuela will go into service Saturday, according to the Ministerio de Comercio Exterior.
This is the second official crossing at the Nicaraguan border.
The immigration services will start slowly there and improve as more facilities are opening, the ministry said.
The government plans no official ceremony Saturday.
Jhon Fonseca, a vice minister, said that opening the border crossing is one of the most important achievements of the Luis Guillermo Solís administration.
The location is expected to provide an international exit from Costa Rica by trucks carrying cargo from the port of Moin. APM
Terminals is building a $1 billion container handling facility there, and a second firm said it also will build a dock setup for cargo from the sea.
The money to construct the buildings at the Las Tablillas crossing came from the exit taxes paid by those leaving the country by land in 2014, said the ministry.