An assassin appears to have been waiting for two men when they arrived at a Pozos de Santa Ana home Saturday night.
The men, who were on a motorcycle, were greeted with bullets as they arrived.
The Judicial Investigating Organization said that a 32-year-old man with the last name of Palacios died at the scene and that his companion, a 29 year old with the last name of López, died on arrival at Hospital San Juan de Dios.
The shooting happened about 7:45 p.m., agents said.
Agents who entered the home said they found a 15 year old there and also five one kilo packages of marijuana.
There also was a 9-mm. pistol and a silencer, agents said.
Palacio had only lived at the location for about a month, agents said.